Always walking with happiness hormons to help if you are down
Well you can tell by my bind to tubulin
This motor protein ain’t stoppin’
Walkin’ the line from A to B
Replenishing the ATPAnyone have the variant with the pimp hat and cane twirling?
WHY would they not sync the step with the beat 😩
Because they probably don’t understand even basic music theory. Unfortunately far too many people don’t.
This made my day, thank you.
Why no Johnny Cash?
Also delivering unhappiness hormone
Kinesin doesn’t discriminate
You have to imagine him enjoying himself.
“But I would walk 500 miles
And I would walk 500 more
Just to be the protein who walks a thousand miles
To deliver cargo to your core” ♫Do they move this slowly? Or is this animation in bullet time?
IIRC it’s like 10.000 times faster (I can be wrong but then it’s probably way faster).
I guess this depends on environmental conditions such as
- temperature
- acidity of the internal cell environment
- how available is energy? My guess this mechanism is powered by ATP?
This animation isn’t just sped up, it’s also simplified. In reality they don’t take steady, purposeful steps. They spaz out with random vibrations (Brownian motion) until the “foot” clicks into place by random chance, then the other one releases and the process repeats. It’s like shaking a container filled with legos until they assemble themselves. The proteins are just shaped in such a way that “walking” is the most probable outcome.
The animation is actually slowed down. Kinesin can take something like 100 steps per second. Each step is about 8 nm, and they’ve been observed to move 600-1000 nm per second.
In reality it wiggles around in Brownian motion but the equilibrium of it “clicking” into place is so attractive that it keeps happening really fast.
Also nice from Neurocience Utrecht
The real Sisyphos
Making my way downtown
We always keep moving forward. No matter what.
When you walkin’
When you walkin’
