• WalnutLum@lemmy.ml
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    2 months ago

    I’m confused where this zeitgeist about Tylenol being bad for you is coming from. I remember working in pharmacy that taking Acetaminophen was the least reactive painkiller with the least number of long-term issues, but I’m hearing a lot more people talking about how bad it is for you.

    The studies I’ve seen have been correlative at best, and, considering that NSAIDs and opioid painkillers are far worse over time, I don’t understand the dissonance in advice that seems to be appearing.

    Is this more “seed oil” nonsense?

    • morbidcactus@lemmy.ca
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      2 months ago

      It’s pretty easy to overdose on Acetaminophen, Wikipedia suggests >100k a year in the us (it’s in so many OTC medication, stuff like cough syrups and the like, really easy to hit the 4g/day max dose)

      I’ll still use it, just use it responsibly.

      • Entertainmeonly@lemmy.blahaj.zone
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        2 months ago

        To add to this I’ve heard professionals in my field say if acetaminophen was discovered today it would likely be a controlled substance for this reason alone. The overdose potential is too high. That always seemed like an extreme measure but i can understand it.

        • Fenderfreek@lemmy.world
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          2 months ago

          It’s more tightly controlled outside the US, in my experience. I think other heath agencies are quite aware of its risks

    • chaitae3@lemmy.world
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      2 months ago

      I don’t follow this topic regularly and I can’t say anything about the mechanisms. From a superficial search I would claim that there is good evidence that Tylenol use during pregnancy can make the development of asthma in the child more likely. There is also some indication (at least one large cohort study from Icahn medical school) that it may cause delayed language development.

      That would be enough evidence for me to discourage use during pregnancy for treatment of discomfort or light pain, when safer options can be tried.

      • WalnutLum@lemmy.ml
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        2 months ago

        My point is that comparatively, acetaminophen is (or at least was) the safest drug for light pain.

        I haven’t seen any new categories of painkiller that would indicate that’s no longer the case, though.

        • jj4211@lemmy.world
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          2 months ago

          So what’s the deal with ibuprofen, naproxen, and aspirin? Seems every time the subject may come up with a doctor, they say ibuprofen to me (last time it came up was when I had to pass a kidney stone, and boy I think I could’ve used an opiate for that one time…).

          Certainly a dramatic swing from 15 years ago when having a sonewhat sore throat during a physical landed me a prescription for opiate cough syrup…

          • WalnutLum@lemmy.ml
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            2 months ago

            NSAIDs cause crazy increased risk of intestinal bleeding and and it inhibits the ability for the kidneys to excrete uric acid, they also increase the risk of heart attack and stroke.

    • TotallynotJessica@lemmy.blahaj.zone
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      2 months ago

      A lot of common over the counter drugs like Tylenol are more risky than people assume, so the idea of one having negative effects on fetal development isn’t out of left field. At the same time, not a single study pushed by this anti science ideologue can ever be trusted without corroboration by independent researchers. The risk of having a bad reaction to common medication nobody bats an eye at is often higher than the vaccines this dumbass rails against, so it’s not like a stopped clock being almost right makes up for his bullshit.

      • CeeBee_Eh@lemmy.world
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        2 months ago

        so it’s not like a stopped clock being almost right makes up for his bullshit.

        Nice try, Jessica